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Table 2 Comparison of our results generated from the dataset of Lee et al. to randomly assigned TF-gene pair lists for functional enrichment and prevalence of protein-protein interaction validation.

From: Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data

 

Lee et al.

 

This study

Random result

One-tailed p -value

Functional enrichment

42/46

31.84 ± 3.28

3.11E-27 (t = -21.87)

Prevalence of PPI

34/46

13.82 ± 3.21

1.48E-41 (t = -44.43)

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BMC Systems Biology

ISSN: 1752-0509

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