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Table 2 Pathway analysis for the eight alternative splicing isoforms.

From: Novel alternative splicing isoform biomarkers identification from high-throughput plasma proteomics profiling of breast cancer

PathwayID

PathwayName

Molecule

200017

p73 transcription factor network

BRCA2;EP300

200141

FOXM1 transcription factor network

EP300;BRCA2

200200

Validated targets of C-MYC transcriptional repression

EP300;ERBB2

hsa04520

Adherens junction

ERBB2;EP300

hsa05212

Pancreatic cancer

ERBB2;BRCA2

1306955

GRB7 events in ERBB2 signaling

ERBB2

1358803

Downregulation of ERRB2:ERBB3 signaling

ERBB2

168253

Host Interactions with Influenza Factors

PBRM1

168268

Virus Assembly and Release

PBRM1

168270

Fusion and Uncoating of the Influenza Virion

PBRM1

168275

Entry of Influenza Virion into Host Cell via Endocytosis

PBRM1

168303

Packaging of Eight RNA Segments

PBRM1

168330

Viral RNP Complexes in the Host Cell Nucleus

PBRM1

192814

vRNA Synthesis

PBRM1

192869

cRNA Synthesis

PBRM1

200159

ErbB receptor signaling network

ERBB2

168277

Influenza Virus Induced Apoptosis

PBRM1

168288

Fusion of the Influenza Virion to the Host Cell Endosome

PBRM1

168298

Release

PBRM1

168302

Budding

PBRM1

168336

Uncoating of the Influenza Virion

PBRM1

192905

vRNP Assembly

PBRM1

73951

Homologous recombination repair of replication-independent double-strand breaks

BRCA2

918233

TRAF3-dependent IRF activation pathway

EP300

73888

Homologous Recombination Repair

BRCA2

76003

Presynaptic phase of homologous DNA pairing and strand exchange

BRCA2

76010

Homologous DNA pairing and strand exchange

BRCA2

h_hifPathway

Hypoxia-Inducible Factor in the Cardiovascular System

EP300

h_pitx2Pathway

Multi-step Regulation of Transcription by Pitx2

EP300

h_ppargPathway

Role of PPAR-gamma Coactivators in Obesity and Thermogenesis

EP300

h_RELAPathway

Acetylation and Deacetylation of RelA in The Nucleus

EP300

hsa05200

Pathways in cancer

ERBB2;BRCA2;EP300

h_carm1Pathway

Transcription Regulation by Methyltransferase of CARM1

EP300

h_melanocytepathway

Melanocyte Development and Pigmentation Pathway

EP300

h_pelp1Pathway

Pelp1 Modulation of Estrogen Receptor Activity

EP300

h_vdrPathway

Control of Gene Expression by Vitamin D Receptor

EP300

hsa05215

Prostate cancer

ERBB2;EP300

h_il7Pathway

IL-7 Signal Transduction

EP300

168325

Viral Messenger RNA Synthesis

PBRM1

1963640

GRB2 events in ERBB2 signaling

ERBB2

419524

Fanconi Anemia pathway

BRCA2

73890

Double-Strand Break Repair

BRCA2

416572

Sema4D induced cell migration and growth-cone collapse

ERBB2

h_g2Pathway

Cell Cycle: G2/M Checkpoint

EP300

h_mef2dPathway

Role of MEF2D in T-cell Apoptosis

EP300

h_atrbrcaPathway

Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility

BRCA2

h_her2Pathway

Role of ERBB2 in Signal Transduction and Oncology

EP300

h_nthiPathway

NFkB activation by Nontypeable Hemophilus influenzae

EP300

h_p53hypoxiaPathway

Hypoxia and p53 in the Cardiovascular system

EP300

h_tgfbPathway

TGF beta signaling pathway

EP300

1250196

SHC1 events in ERBB2 signaling

ERBB2

200025

Signaling events mediated by HDAC Class III

EP300

hsa03440

Homologous recombination

BRCA2

200164

Retinoic acid receptors-mediated signaling

EP300

400685

Sema4D in semaphorin signaling

ERBB2

933541

TRAF6 mediated IRF7 activation

EP300