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Table 4 Top 20 prediction result generated from cMap using GSE4025 E2 treatment signature as a query

From: BRCA-Monet: a breast cancer specific drug treatment mode-of-action network for treatment effective prediction using large scale microarray database

Rank

Cmap name

Mean

N

Enrichment

P

Specificity

1

MS-275

-0.954

2

-1.000

0.00000

0.0217

2

Vorinostat

-0.697

12

-0.855

0.00000

0.0266

3

Trichostatin A

-0.597

182

-0.735

0.00000

0.0000

4

Cephaeline

-0.564

5

-0.889

0.00006

0.0361

5

Scriptaid

-0.701

3

-0.962

0.00018

0.0000

6

Prochlorperazine

-0.276

16

-0.506

0.00018

0.0472

7

Mefloquine

-0.481

5

-0.805

0.00064

0.0278

8

5252917

0.657

2

0.977

0.00087

0.0000

9

Raloxifene

-0.465

7

-0.670

0.00114

0.0130

10

perhexiline

-0.476

4

-0.821

0.00193

0.0168

11

Ceforanide

0.199

4

0.813

0.00235

0.0207

12

Bacitracin

0.516

3

0.890

0.00252

0.0068

13

Ikarugamycin

-0.525

3

-0.886

0.00292

0.0152

14

Iloprost

0.353

3

0.876

0.00354

0.0197

15

Isoxican

0.290

5

0.722

0.00375

0.0549

16

Diethylstilbestrol

0.413

6

0.666

0.00399

0.0737

17

Bufexamac

-0.404

4

-0.786

0.00426

0.0000

18

Norcyclobenzaprine

-0.404

4

-0.778

0.00501

0.0310

19

Riboflavin

-0.412

4

-0.777

0.00511

0.0000

20

arachidonyltrifluoromethane

0.576

2

0.946

0.00535

0.0000