From: GeneTopics - interpretation of gene sets via literature-driven topic models
GAD gene set | LDA model # | Relevant number of topics | Best Topic |
---|---|---|---|
esophageal cancer | 20 | 7 | genotyp,polymorph,risk,associ,cancer,95,gstm1,gene,or,ci,control,studi,allel,gstt1,p,patient,genet,gstp1,frequenc,signific |
kidney cancer | 15 | 2 | polymorph,xrcc1,risk,repair,cancer,genotyp,dna,95,associ,ci,gene,allel,variant,control,patient,suscept,breast,frequenc,case,ratio |
Alzheimer's disease | 15 | 10 | polymorph,genotyp,associ,allel,risk,gene,patient,p,popul,genet,95,variant,diseas,haplotyp,diabet,subject,frequenc,ci,snps,control |
blood pressure, arterial | 20 | 11 | polymorph,genotyp,gene,associ,allel,p,risk,variant,hypertens,patient,genet,subject,popul,95,haplotyp,frequenc,ci,variat,studi,pressur |
carotid atherosclerosis | 10 | 6 | eno,endotheli,ace,oxid,rat,inhibitor,nitric,group,renal,p,inhibit,day,treatment,synthas,after,vascular,arteri,heart,angiotensin,enzym |
hypertension | 20 | 14 | arteri,rat,angiotensin,pressur,vascular,hypertens,heart,cardiac,receptor,renal,blood,ang,increas,ace,endotheli,ventricular,express,after,at1,muscl |
cirrhosis | 10 | 5 | iron,transferrin,receptor,tfr,hfe,ferritin,cell,stfr,method,uptak,serum,assay,status,sampl,antibodi,marrow,recycl,blood,concentr,defici |
hepatitis c, chronic | 10 | 7 | polymorph,il12b,genotyp,associ,allel,risk,gene,frequenc,patient,haplotyp,genet,diseas,suscept,p,popul,asthma,ci,il12,variant,95 |
longevity | 15 | 7 | polymorph,genotyp,gstm1,gene,risk,associ,gstt1,cancer,allel,frequenc,genet,95,null,ci,patient,control,variant,popul,individu,p |
diabetes, type 2 | 20 | 14 | polymorph,associ,genotyp,gene,allel,p,risk,diabet,variant,patient,subject,genet,popul,snps,type,frequenc,haplotyp,95,2,studi |