Table 1 Topics found for KEGG Metabolic pathways
From: GeneTopics - interpretation of gene sets via literature-driven topic models
KEGG Id | Pathway Name | LDA model # | Best Topic | pvalue | Topic words (stemmed) |
|---|---|---|---|---|---|
hsa00010 | Glycolysis / Gluconeogenesis | 25 | Topic11 | 6.60E-23 | strain,acet,mutant,acid,growth,glucos,cerevisia,plant,yeast,enzym,ferment,synthetas,coli,acetylcoa,gene,product,encod,activ,saccharomyc,ac |
hsa00020 | Citrate cycle (TCA cycle) | 10 | Topic7 | 1.87E-08 | mitochondri,activ,enzym,oxid,aconitas,b5,dehydrogenas,reductas,cytochrom,malat,inhibit,mitochondria,reduct,nadhcytochrom,b5r,alphaketoglutar,cytosol,kgdhc,citrat,inactiv |
hsa00030 | Pentose phosphate pathway | 25 | Topic7 | 1.82E-12 | enzym,activ,pfk,fructos,inhibit,ph,purifi,atp,subunit,concentr,pfk1,kinet,degre,aldolas,alloster,affin,kda,molecular,appar,purif |
hsa00040 | Pentose and glucuronate interconversions | 25 | Topic19 | 1.20E-20 | glucuronid,human,ugt,liver,microsom,ugt2b7,activ,udpglucuronosyltransferas,ugt1a9,ugt1a6,ugt1a4,substrat,ugt1a1,isoform,ugt1a3,ugt1a10,valu,acid,express,format |
hsa00051 | Fructose and mannose metabolism | 25 | Topic19 | 1.58E-10 | fructos,fructokinas,activ,enzym,pmm,sugar,plant,phosphoryl,khk,sucros,substrat,mannos,l,km,character,glucos,ketohexokinas,gene,clone,metabol |
hsa00052 | Galactose metabolism | 25 | Topic14 | 3.05E-09 | mutat,diseas,patient,defici,gene,caus,allel,clinic,storag,case,acid,glycogen,type,muscl,identifi,disord,or,genet,polymorph,lysosom |
hsa00053 | Ascorbate and aldarate metabolism | 50 | Topic2 | 1.60E-13 | glucuronid,human,ugt,liver,microsom,activ,ugt2b7,udpglucuronosyltransferas,ugt1a9,substrat,ugt1a1,valu,ugt1a6,ugt1a3,ugt1a4,metabol,enzym,kinet,microm,inhibit |
hsa00062 | Fatty acid elongation | 10 | Topic9 | 1.53E-08 | peroxisom,enzym,dehydrogenas,hydratas,activ,acid,thiolas,betaoxid,enoylcoa,acylcoa,fatti,coli,3ketoacylcoa,prolin,p5cdh,substrat,liver,coa,oxid,catalyz |
hsa00071 | Fatty acid metabolism | 50 | Topic19 | 1.76E-16 | enzym,activ,substrat,structur,dehydrogenas,residu,bind,site,catalyt,acid,mutant,dhdps,coli,specif,reaction,inhibit,form,studi,kinet,differ |
hsa00100 | Steroid biosynthesis | 10 | Topic4 | 6.45E-10 | cholesterol,acat2,ester,acat,lipas,acat1,esteras,intestin,lipoprotein,lipid,cholesteryl,ldl,acyltransferas,liver,mice,cel,pancreat,plasma,bile,acid |