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Table 1 Modules identified when only somatic mutations and gene expressions are used

From: Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data

Module

Gene

p-value for exclusivity

Related to GBM

Reference

1

EGFR, NF1, PTEN, PIK3R1, TP53

0.01

all the genes

[49] and the references wherein

2

COL6A2, DST, ERBB2, PIK3CA, RB1

< 0.001

all except DST

same as above

3

PRAME, SYNE1

< 0.001

both genes

same as above

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BMC Systems Biology

ISSN: 1752-0509

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