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Table 4 The 10 most robust viable phenotypes

From: Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model

Rank

Strain name

Phenotype

Percent of total losses

34

TAB6-1 CLB1 clb2 Δ

Viable

0.51

36

GAL-SIC1

Viable

0.53

37

GAL-NET1 GAL-CDC14

Viable

0.53

39

Multicopy CDC15

Viable

0.57

40

GAL-TEM1

Viable

0.60

41

WT in glucose

Viable

0.61

42

WT in galactose

Viable

0.62

43

ppx Δ

Viable

0.62

44

TAB6-1

Viable

0.62

45

tem1-ts multicopy CDC15

Viable

0.62

  1. These are the viable phenotypes that are least often lost (i.e., incorrectly simulated) when perturbations are applied to individual model parameters. Robustness decreases from top to bottom. TAB6-1 has lowered efficiency of Cdc14-Net1 complex (RENT) formation compared to WT efficiency.