Figure 5From: Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle modelEffects of population size and criterion used in LH sampling on the optimization. Increase in the number of mutants captured during independent DE runs for population sizes N = 19 (green lines) and N = 27 (blue lines). Pink line: Model performance for the initial guess for the parameter vector (O = 72 hits; O max = 119). Red line: WT viability in glucose is not enforced during LH sampling phase.Back to article page