Table 1 GEO datasets used in the meta-analysis
GEO dataset | ADC source of cases | Group description | Braak stage | Age | Brief summary of findings |
|---|---|---|---|---|---|
GSE28146 | University of Kentucky | Control | 2.3 ± 0.4 | 85.3 ± 2.7 | Down regulation of molecules that stabilize ryanodine receptor Ca2+ release |
Severe AD | 5.8 ± 0.2 | 84.0 ± 4.0 | Up regulation of vasculature development | ||
GSE5281 | Arizona, Duke University, Washington University | Not AD | 1.2 ± 0.1 | 79.6 ± 2.6 | Mitochondrial and electron transport dysfunction |
Definite AD | 5.3 ± 0.2 | 77.8 ± 1.8 | Expression changes of metabolism-related genes |