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Table 8 Split ratios of L-glutamate discounting transamination cycles

From: A metabolite-centric view on flux distributions in genome-scale metabolic models

Producing fluxes

Reaction

Pathway

Ratio

glutamate dehydrogenase

TCA cycle

100%

Consuming fluxes

Reaction

Pathway

Ratio

N-acetylglutamate synthase

Arg, polyamines

30.10%

glutamine synthetase

Gln

23.51%

Biomass

 

23.51%

glutamate 5-kinase

Pro

19.75%

glutamate racemase

peptidoglycans

2.54%

glutamyl-tRNA synthetase

cobalamin, heme

0.49%

dihydrofolate synthase

folate metabolism

0.08%

  1. Total flux: 0.93 mmol gDW−1 h−1. Ratios below 0.05% not shown.
  2. Abbreviations: Arg, Gln, Pro – biosynthesis of L-amino acids.