From: Function and design of the Nox1 system in vascular smooth muscle cells
Subunit distribution in RtRS | Responsiveness to representative signals |
---|---|
[p47phox] = 0; [Rac1GDP] = 0; | No response to S1, S2, or S1 & S2 |
[p47phox] = 0; [Rac1GDP] = 1; | Response to S2, and S1 & S2, but no response to S1 |
[p47phox] = 1; [Rac1GDP] = 0; | Response to S1, and S1 & S2, but no response to S2 |
[p47phox] = 1; [Rac1GDP] = 1; | Response only to S1 & S2, but not to S1 or S2 |