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Figure 2 | BMC Systems Biology

Figure 2

From: A kinetic model for RNA-interference of focal adhesions

Figure 2

Scheme of the kinetic model. The overall model scheme reveals the main design principles. The mRNA transcription and degradation are depicted on the left hand side. After the translation of the proteins, these are assembled to focal complexes (ACI). Focal complexes can in turn mature to focal adhesions (ACI#). The assembly process is regulated by Rac and the maturation process is regulated by force and Rho. Depending on the force model used, the reactions marked with a star are either promoting (slip bonds) or suppressing (catch bonds) focal adhesion or focal complex disassembly.

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