Skip to main content

Table 2 Comparison of mass action ratios of central carbon metabolism reactions under different cultivation conditions

From: Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary 13C flux analysis

Enzyme

Mass action ratios

P. pastoris

S. cerevisiae

  

Glucose-methanol

Glucose a

Glucose b

PGI

Fru6P/Glc6P

0.22 ± 0.03

0.22 ± 0.11

0.26 ± 0.00

PMI

Man6P/Fru6P

0.36 ± 0.08

1.27 ± 0.06

1.18 ± 0.01

ENO

Pep/PG2

3.3 ± 0.29

1.67 ± 0.10

4.01 ± 0.09

FMH

MAL/FUM

3.7 ± 2.15

5.25 ± 0.38

5.15 ± 0.14

  1. aData taken from [11].
  2. bData taken from [40].
  3. PGI, Phosphoglucose Isomerase, PMI, Phosphomannose Isomerase; ENO, Enolase; FMH, Fumarase.