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Figure 4 | BMC Systems Biology

Figure 4

From: A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis

Figure 4

Broken Path Analysis of the protein- protein interaction network. Effect of a KO in the network was determined by calculating the percentage disruption in the network based on the number of paths perturbed. The plot represents the% disruption of each gene knockout on the y- axis, while x - axis represents the gene index sorted based on p values. Also shown is the significance star for the genes based on the p values calculated using random networks.

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