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Figure 1 | BMC Systems Biology

Figure 1

From: Knowledge-based compact disease models identify new molecular players contributing to early-stage Alzheimer’s disease

Figure 1

A. Tier 0 and Tier (1 + 2) genes differentially expressed in Alzheimer’s disease and other neuropathies are compared with significantly expressed random genes on Illumina platform, dataset C. Tier 0 is produced by an overlap of Tier (1 + 2) in Alzheimer’s disease panel (Datasets A and B) with the multiple neurodegeneration disease panel (Dataset C). Tier (1 + 2–0) is produced by the balance of Tier (1 + 2) genes with the subtraction of Tier 0. Random genes ranked by intensity were sampled based on the position in the rank. Expression intensities in the groups of genes formed as described above were measured and plotted.

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BMC Systems Biology

ISSN: 1752-0509

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