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Figure 3 | BMC Systems Biology

Figure 3

From: Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress

Figure 3

The expression of predicted target genes for HrcA (A) and CtsR (B). The putative regulon structure is shown for HrcA (C) and CtsR (D) (see text for details). Genes in each listed operon are shown by arrows; TF genes are in black, chaperone proteins are in light grey; potential novel genes for a regulon in C. acetobutylicum are in dark grey; presence of TF binding sites are indicated by black circles. The sequence logos (which represent sequence conservation) for HrcA and CtsR binding motifs in C. acetobutylicum are shown in (C) and (D), were created with 6 and 5 binding sites respectively, using WebLogo [37, 38]. Gene expression data are displayed as in fold change compared to no-stress control cultures at the same timepoint.

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