Table 1 List of 81 covariates used in analysis

Allergen screen

**FoodScreen (5 food allergens)

kUA/L

**Phadiatop (15 aeoallegens)

kUA/L

Total Serum IgE

kU/L

Blood Chemistry

C-reactive Protein

mg/ml

Albumin

g/dL

Alkaline Phosphatase

IU/L

Serum Glutamic Pyruvic Transaminase

IU/L

Serum Aspartate Aminotranferase (AST) Serum Glutamic-Oxaloacetic Transaminase (SGOT)

IU/L

Albumin/Globulin ratio

Serum Total Bilirubin

mg/dL

Serum Blood Urea Nitrogen

mg/dL

Serum Blood Urea Nitrogen Creatinine Ratio

Serum Calcium

mg/dL

Serum Chloride

mmol/L

Serum Creatinine

mg/dL

Serum Ferritin

ng/ml

Serum Fibrinogen

mg/dL

Serum Gamma-Glutamyl Transpeptidase (GGT)

IU/L

Serum Total Globulin

g/dL

Blood Hematocrit

%

Blood Hemoglobin

g/DdL

Serum Iron

ug/dl

Serum Lactate Dehydrogenase

IU/L

Plasma Leptin

ng/ml

Serum Glycated Hemoglobin

%

Serum Glucose

mg/dL

Potassium

mmol/L

Urine Creatinine

mg/dl

Serum Arachidonic Acid

ug/ml

Serum Osmolality

mOsmol/kg

Serum Phospholipids Concentration

Mg/dL

Serum Phosphorus

mg/dL

Serum Total Protein

g/dL

Sodium

mmol/L

BP Oxygen Saturation (Dissolved Oxygen)

%

CBC

White Blood Cell Count

K/uL

Basophil percent of sum White Blood Cells

%

Eosinophil percent of sum White Blood Cells

%

Lymphocyte percent of sum White Blood Cells

%

Monocyte percent of sum White Blood Cells

%

Neutrophils percent of sum White Blood Cells

%

Clinic

Subject Age

Years

Subject Height

Cm

Subject Body Mass Index Weight/height

kg/m²

Subject Weight

Kg

Mean of first Two Diastolic Blood Pressure Measurements

mmHg

Mean of first two Systolic Blood Pressure Measurements

mmHg

Blood Pressure Pulse

beats/min

Hematology

Red Blood Cell Count

M/uL

Platelet Count

K/uL

Mean Corpuscular Hemoglobin

Pg

Mean Corpuscular hemoglobin concentration

g/dL

Mean Corpuscular Volume

fL***

Red Blood Cell Distribution Width

%

Inflammatory

Interleukin-4

pg/ml

Serum Total Antioxidant Status

mmol/L

Serum Unbound Iron-Binding Capacity

ug/dl

Serum Uric Acid

mg/dL

Plasma Average of Reactive Oxygen Species Measurements minus Control

RLU****

Lipids

High density Lipoprotein

mg/dL

Low density Lipoprotein

mg/dL

Total Cholesterol to High density Lipoprotein Ratio

Total Cholesterol

mg/dL

Serum Triglycerides

mg/dL

Very Low Density Lipoprotein

mg/dL.

Lung Function

Forced Expiratory Flow Between 25% and 75% of Forced Expiratory Flow

Fractional Exhaled Nitric Oxide

ppb

Forced Expiratory Volume /ratio to Forced Vital Capacity

%

Peak Expiratory Flow

(L/min)

Serum Allergens

*Serum Alternaria Alternata

kUA/L

*Serum Aspergillus Fumigatus

kUA/L

*Serum Cat Dander Epithel

kUA/L

*Serum Cladosporium Herbarum

kUA/L

*Serum Derm Farin Dustmite

kUA/L

*Serum Derm Pter Dustmite

kUA/L

*Serum Dog Dander

kUA/L

*Serum German Cockroach

kUA/L

*Serum Mouse Urine Protein

kUA/L

*Serum Penicillium Notatum

kUA/L

*Serum Rat Urine Protein

kUA/L