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Table 1 Parameter values

From: A model of HIV drug resistance driven by heterogeneities in host immunity and adherence patterns

Parameter

Value

Units

Ref

Parameter

Value

Units

Ref

v SS

51,000

copies mL -1

[32]

m WT

1.139

Unitless

[46]

λ

105

cells mL-1day-1

[32]

m K65R

1.126

Unitless

[46]

b

0.027

day -1

[32]

IC 50 ,WT

0.050*

μg mL -1

[46]

d

0.1

day -1

[32]

IC 50 ,K65R

2.2*

μg mL -1

[46]

u

5

day -1

[32]

K a

14.64

day -1

[41]

a

0.5

day -1

[32]

K e

9.6

day -1

[41]

c 1

1000

cells mL-1day-1

[32]

K 1f

9.6

day -1

[41]

β

2f × 105

mL count-1day-1

[32]

K 1b

30.3

day -1

[41]

f

Variable (Equation 9)

Unitless

 

K 2f

270.7

day -1

[41]

h

0.002

day -1

[41]

K 2b

95.5

day -1

[41]

w ss /y ss (for g )

0.39

Unitless

[72]

K m

24000

day -1

[41]

k WT

100/f

day -1

[32]

K c

1.1

day -1

[41]

k K65R

61.054/f

day -1

[46]

f plasma-bound

0.07

Unitless

[41]

H

1800

Unitless

[42]

* Concentration in plasma.