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Figure 3 | BMC Systems Biology

Figure 3

From: A novel neural response algorithm for protein function prediction

Figure 3

Detailed workout of CHD1. (a) Query sequence CHD1 is scanned for the potential template hits. (b) Computation of the corresponding neural response. (c) Calculation of pair wise neural response N(p, q j ) viz. (CHD1-AAAS), (CHD1-CHD2) and (CHD1-CDV3). (d) Database of pre-computed neural response for the base dataset. (e) The pair wise pair wise neural response vectors are fed to the mapping function using a Gaussian kernel to generate a value ranging from 0 to 1. (f) Proteins in the base dataset ate sorted in descending order based on their similarity (f(N (i, j) )) to the query protein. (g) GO term GO:0005524 of CHD2, with high mapping score is assigned to CHD1.

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