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Figure 2 | BMC Systems Biology

Figure 2

From: Characterizing criticality of proteins by systems dynamics: Escherichia coli central carbon metabolism as a working example

Figure 2

System state fluctuations caused by enzyme deletions. The impacts of enzyme deletions on system states are shown. In all subfigures, x-axis: state variable (metabolite) indexes (denoted as "Metab", see Additional file 6 for details); y-axis: distance of state variable from the deleted enzyme ("Dist"); z-axis: the impact amplitude ("Amp"). (A - D) The influences of TKb, PGK, TIS, and PGI deletions on system state, respectively. The figures exemplify that an enzyme can affect distant metabolites even greater than its closest neighbours.

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BMC Systems Biology

ISSN: 1752-0509

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