Table 1 Detailed information about the DETFs
DETF | Cluster | Associated biological processes |
|---|---|---|
Atf3 | 5 | gluconeogenesis; regulation of cell proliferation |
Cebpa | 4 | liver development; fat cell differentiation; regulation of cell proliferation; urea cycle |
Cebpb | 6 | cell differentiation; anti-apoptotic |
Cebpd | 4 | fat cell differentiation |
Csrnp1 | 5 | apoptotic process; platelet-derived growth factor receptor signaling pathway |
Dbp | 6 | rhythmic processes |
E2f6 | 2 | regulation of transcription involved in G1/S phase of mitotic cell cycles; |
Egr1 | 6 | BMP signaling; Il1 mediated signaling pathway; regulation of Wnt signaling pathway; regulation of cell-death; response to glucose stimulus; response to insulin stimulus |
Fos | 6 | cellular response to extracellular stimuli; response to stress |
Foxa1 | 2 | glucose homeostasis; chromatin remodeling |
Gatad1 | 2 | - |
Id3 | 3 | regulation of cell cycle; regulation of apoptosis |
Irf1 | 3 | cellular response to Il1; regulation of cell-death |
Klf16 | 6 | - |
Maff | 5 | epidermal cell-differentiation |
Nr1h4 | 2 | bile acid metabolic process; regulation of carbohydrate- and urea metabolic process; |
Ppara | 4 | Glucose metabolic process; lipid metabolic process; response to insulin stimulus |
Srebf1 | 4 | Steroid metabolic process; response to glucose stimulus; lipid metabolic process; |
Srf | 4 | actin filament organization; cell-cell adhesion; developmental growth; |
Tgif1 | 3 | regulation of cell proliferation; regulation of retinoic acid receptor signaling pathway |
Tsc22d1 | 2 | regulation of apoptotic process; regulation of cell proliferation |
Zbtb16 | 4 | positive regulation of apoptosis; negative regulation of proliferation |