From: Incremental parameter estimation of kinetic metabolic network models
Simultaneous method | Incremental method | |||
---|---|---|---|---|
| min Φ S | min Φ C | min Φ S | |
CPU time (sec) | >5 days | 3476.89 ± 349.63 | 976.72 ± 31.01 | 20.82 ± 2.71 |
eSSM GO iterations | — | 1662 ± 282 | 4 ± 1 | 33 ± 7 |
Φ C | — | Stiff ODE | 2.20 ± 8.81 × 10-3 | 6.18 ± 7.28 × 10-2 |
Φ S | — | 2.67 ± 1.93 × 10-4 | 1.51 × 103 ± 52.50 | 5.79 ± 9.62 × 10-4 |