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Figure 2 | BMC Systems Biology

Figure 2

From: Simplification of biochemical models: a general approach based on the analysis of the impact of individual species and reactions on the systems dynamics

Figure 2

Michaelis Menten model. Left: M r → 0 (S0 = 100; E0 = 1; k1 = 1; k-1 = k2 = 100). Right: S t → 0 (S0 = 100; E0 = 100; k1 = k-1 = 100; k2 = 1). Time evolution of the Radical Pointer (RP) in the fast mode (top), Participation Indexes (PI) of reactions R1 and R2 in the fast (middle) and slow mode (bottom). The RP of product P in the first case M r → 0 is similar to RP of substrate S (the both lines overlaid).

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