Figure 2From: Simplification of biochemical models: a general approach based on the analysis of the impact of individual species and reactions on the systems dynamicsMichaelis Menten model. Left: M r → 0 (S0 = 100; E0 = 1; k1 = 1; k-1 = k2 = 100). Right: S t → 0 (S0 = 100; E0 = 100; k1 = k-1 = 100; k2 = 1). Time evolution of the Radical Pointer (RP) in the fast mode (top), Participation Indexes (PI) of reactions R1 and R2 in the fast (middle) and slow mode (bottom). The RP of product P in the first case M r → 0 is similar to RP of substrate S (the both lines overlaid).Back to article page