Computational codon optimization of synthetic gene for protein expression

BMC Systems Biology

Table 2 Tournament matrix

	x _ICO	x _CCO	x _MOCO	x _RCA
		7	19	95
		2	18	99
x _ICO		4	15	93
		5	22	99
	92		82	97
	96		93	100
x _CCO	96		86	100
	93		89	99
	78	15		97
	74	5		100
x _MOCO	83	12		99
	75	9		99
	5	2	3
	0	0	0
x _RCA	6	0	1
	1	0	0

For every gene, the p_M of the optimal sequences generated by respective optimization approaches are compared pair-wise for each expression host. The numbers of tournament wins/losses by each approach for all the genes in each expression host are added up. The sequences generated by ICO, CCO, MOCO and RCA are indicated as x_ICO, x_CCO, x_MOCO and x_RCA respectively. In each cell, the numbers from top-most to bottom-most corresponds to the data for E. coli, L. lactis, P. pastoris and S. cerevisiae, respectively.

ISSN: 1752-0509