Skip to main content
Figure 7 | BMC Systems Biology

Figure 7

From: Gene autoregulation via intronic microRNAs and its functions

Figure 7

Classification of miRNAs and randomization results. (A) Classification of human miRNAs based on the percentage of intergenic and intragenic miRNAs. Intragenic miRNAs are divided in exonic and intronic miRNAs and each group can be further classified as same strand or opposite strand. All UTR miRNAs were included in the group of the exonic miRNAs. Data are reported in Table S1 of Additional file1. (B) Number of intronic miRNA-mediated self-loops as a function of the number of target prediction methods in agreement: we found a total of 77 iMSLs predicted by at least one prediction methods, 25 of them are predicted by at least two different methods and only three of them are predicted by 5 different methods. (C) Results of the permutation test: the number of iMSLs in the human network is plotted as a dashed line alongside the distributions (normalized histograms) of the number of iMSLs found using the two randomization strategies (described in the main text) over 1000 experiment repetitions.

Back to article page