From: A comprehensive network and pathway analysis of candidate genes in major depressive disorder
GO terms | Observed* | P | P BH $ |
---|---|---|---|
Biological process | Â | Â | Â |
GO:0007268: synaptic transmission | 45 | 7.18 × 10-38 | 1.18 × 10-34 |
GO:0007267: cell-cell signaling | 56 | 8.78 × 10-37 | 7.21 × 10-34 |
GO:0019226: transmission of nerve impulse | 46 | 2.84 × 10-36 | 1.55 × 10-33 |
GO:0044057: regulation of system process | 36 | 1.23 × 10-29 | 2.89 × 10-27 |
GO:0051239: regulation of multicellular organismal process | 55 | 1.07 × 10-29 | 2.89 × 10-27 |
GO:0050877: neurological system process | 59 | 4.72 × 10-26 | 9.69 × 10-24 |
GO:0007154: cell communication | 103 | 6.14 × 10-26 | 1.12 × 10-23 |
Molecular function | Â | Â | Â |
GO:0008227: G-protein coupled amine receptor activity | 15 | 5.13 × 10-21 | 7.18 × 10-19 |
GO:0035240: dopamine binding | 7 | 2.25 × 10-13 | 1.58 × 10-11 |
GO:0005230: extracellular ligand-gated ion channel activity | 12 | 4.17 × 10-12 | 2.34 × 10-10 |
GO:0004888: transmembrane receptor activity | 40 | 6.55 × 10-12 | 2.78 × 10-10 |
GO:0005102: receptor binding | 31 | 9.87 × 10-11 | 3.07 × 10-9 |
GO:0022834: ligand-gated channel activity | 13 | 2.46 × 10-10 | 5.74 × 10-9 |
Cellular component | Â | Â | Â |
GO:0043005: neuron projection | 30 | 2.43 × 10-22 | 3.91 × 10-20 |
GO:0044459: plasma membrane part | 61 | 3.12 × 10-20 | 2.51 × 10-18 |
GO:0000267: cell fraction | 45 | 1.45 × 10-19 | 7.78 × 10-18 |
GO:0005887: integral to plasma membrane | 47 | 5.84 × 10-19 | 2.35 × 10-17 |
GO:0031226: intrinsic to plasma membrane | 47 | 1.27 × 10-18 | 4.09 × 10-17 |
GO:0042995: cell projection | 35 | 5.50 × 10-18 | 1.48 × 10-16 |
GO:0005886: plasma membrane | 80 | 1.64 × 10-17 | 3.77 × 10-16 |
GO:0030424: axon | 18 | 1.15 × 10-15 | 2.31 × 10-14 |
GO:0030425: dendrite | 17 | 2.76 × 10-14 | 4.94 × 10-13 |
GO:0005626: insoluble fraction | 32 | 7.11 × 10-13 | 1.14 × 10-11 |