Extended local similarity analysis (eLSA) of microbial community and other time series data with replicates

BMC Systems Biology

Table 2 Significant associations found in real datasets

		Found by eLSA	Found by PCC	Found by both	Found by eLSA	Found by PCC	Found by both
Dataset	# of factors	P ≤ 0.01	P ≤ 0.01	P ≤ 0.01	P ≤ 0.05	P ≤ 0.05	P ≤ 0.05
		Q ≤ 0.01	Q ≤ 0.01	Q ≤ 0.01	Q ≤ 0.05	Q ≤ 0.05	Q ≤ 0.05
Microbial	515	1643	3237	293	2804	4242	658
C. elegans	446	42532	56605	39114	57991	71799	54201

Numbers of significant associations found by the extended Local Similarity Analysis (eLSA) and Pearson’s Correlation Coefficient (PCC) by controlling both the p-value (P) and the q-value (Q). The p-values for eLSA were evaluated by permutations and p-values for PCC was calculated based on the t-distribution.

ISSN: 1752-0509