Table 4 Replication of GWAS of highLDLhighTG
SNP | Ansung | Ansan | Combined | Male | Female | Combined | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | LDLTG n=205 | LDL-C n=919 | TG n=936 | LDLTG n=340 | LDL-C n=1352 | TG n=843 | LDLTG n=545 | LDLTG n=288 | LDL-C n=1044 | TG n=969 | LDLTG n=257 | LDL-C n=1227 | TG n=810 | LDLTG n=545 |
rs11700112 | 2.6×10-2 | 0.1818 | 0.3849 | 3.1×10-2 | 0.7172 | 0.0172 | 2.8×10-2 | 1.8×10-1 | 0.4161 | 0.6321 | 1.0×10-3 | 0.0967 | 0.0072 | 9.2×10-2 |
rs6140956 | 8.8×10-4 | 0.1770 | 0.1017 | 7.1×10-2 | 0.7749 | 0.0332 | 3.6×10-2 | 1.1×10-1 | 0.6353 | 0.3125 | 8.4×10-4 | 0.2317 | 0.0096 | 5.6×10-2 |
rs6133716 | 1.8×10-3 | 0.2691 | 0.0748 | 9.3×10-2 | 0.7603 | 0.0701 | 4.7×10-2 | 1.1×10-1 | 0.9550 | 0.2231 | 1.9×10-3 | 0.1757 | 0.0259 | 5.8×10-2 |
rs9967942 | 2.6×10-2 | 0.3476 | 0.4816 | 4.1×10-2 | 0.6707 | 0.0198 | 3.3×10-2 | 4.1×10-1 | 0.2925 | 0.8325 | 6.9×10-4 | 0.1545 | 0.0072 | 2.0×10-1 |
rs11087847 | 1.9×10-2 | 0.1531 | 0.3200 | 3.5×10-2 | 0.7218 | 0.0151 | 2.7×10-2 | 1.5×10-1 | 0.4459 | 0.5424 | 1.1×10-3 | 0.0750 | 0.0062 | 7.4×10-2 |
rs2822994 | 1.1×10-1 | 0.1582 | 0.2536 | 2.9×10-5 | 0.0158 | 0.0019 | 5.4×10-2 | 1.5×10-2 | 0.4400 | 0.0060 | 2.4×10-4 | 0.0045 | 0.1282 | 7.9×10-3 |
rs2822998 | 1.2×10-1 | 0.1985 | 0.2456 | 7.4×10-5 | 0.0172 | 0.0043 | 5.8×10-2 | 3.2×10-2 | 0.4875 | 0.0084 | 2.9×10-4 | 0.0101 | 0.1361 | 1.6×10-2 |
rs1041404 | 1.6×10-3 | 0.0668 | 0.0357 | 3.1×10-3 | 0.0274 | 0.0338 | 2.4×10-3 | 7.8×10-3 | 0.3843 | 0.0049 | 4.4×10-4 | 0.0094 | 0.0939 | 4.1×10-3 |
rs9959874 | 1.2×10-1 | 0.4953 | 0.1942 | 1.1×10-3 | 0.0540 | 0.2536 | 5.9×10-2 | 4.3×10-3 | 0.4620 | 0.0720 | 1.8×10-1 | 0.2007 | 0.9606 | 9.3×10-2 |
rs1893506 | 1.2×10-1 | 0.4953 | 0.1942 | 1.3×10-3 | 0.0584 | 0.2616 | 5.9×10-2 | 5.3×10-3 | 0.4620 | 0.0771 | 1.8×10-1 | 0.2018 | 0.9797 | 9.4×10-2 |
rs4744611 | 1.7×10-2 | 0.9652 | 0.0078 | 4.3×10-2 | 0.0090 | 0.8933 | 3.0×10-2 | 1.1×10-3 | 0.0113 | 0.1925 | 1.8×10-1 | 0.6221 | 0.4880 | 9.1×10-2 |
rs7039780 | 7.8×10-3 | 0.6334 | 0.0107 | 1.4×10-1 | 0.0238 | 0.7387 | 7.6×10-2 | 2.2×10-3 | 0.0080 | 0.2893 | 2.2×10-1 | 0.6317 | 0.4947 | 1.1×10-1 |
rs4744608 | 7.8×10-3 | 0.5846 | 0.0122 | 1.6×10-1 | 0.0253 | 0.6955 | 8.2×10-2 | 1.8×10-3 | 0.0074 | 0.2650 | 2.6×10-1 | 0.6317 | 0.5936 | 1.3×10-1 |
rs665770 | 2.3×10-2 | 0.2715 | 0.3219 | 4.7×10-2 | 0.0747 | 0.3156 | 3.5×10-2 | 1.6×10-2 | 0.5529 | 0.1529 | 8.1×10-2 | 0.0321 | 0.6182 | 4.9×10-2 |
rs529581 | 2.2×10-2 | 0.2498 | 0.3413 | 4.5×10-2 | 0.0524 | 0.3337 | 3.4×10-2 | 2.4×10-2 | 0.5012 | 0.1932 | 6.2×10-2 | 0.0260 | 0.5976 | 4.3×10-2 |
rs693 | 8.0×10-3 | 0.0889 | 0.2148 | 1.1×10-2 | 0.0045 | 0.0396 | 9.6×10-3 | 2.1×10-3 | 0.0373 | 0.0147 | 2.8×10-2 | 0.0056 | 0.6146 | 1.5×10-2 |