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Table 7 Power (when effect size is 0.3 or 0.6) in the simulation studies

From: SNP-PRAGE: SNP-based parametric robust analysis of gene set enrichment

Effect size (=β) Causal gene set Gene set size Gene size significance level Z-statistic method SNP-PRAGE GLOSSI GSEA
      m m   
      1 2 3 4 5 1 2 3 4 5   
0.3 Set1 20
genes
9~12
SNPs
0.05
0.01
.81
.78
.81
.75
.74
.66
.67
.55
.59
.38
.92
.90
.92
.91
.94
.92
.95
.92
.95
.91
.92
.89
.95
.91
  Set3 20
genes
20 ~30
SNPs
0.05
0.01
.85
.76
.78
.75
.79
.74
.79
.74
.76
.73
.81
.71
.81
.73
.83
.73
.82
.74
.83
.74
.82
.72
.83
.71
  Set5 20
genes
36~49
SNPs
0.05
0.01
.98
.95
.99
.97
.99
.97
.99
.99
.99
.98
.74
.61
.74
.62
.75
.62
.75
.62
.76
.63
.74
.60
.73
.61
0.6 Set1 20
genes
9~12
SNPs
0.05
0.01
.84
.80
.83
.75
.78
.69
.69
.60
.62
.48
.97
.94
.98
.95
.98
.97
.98
.97
.97
.96
.98
.96
.98
.97
  Set3 20
genes
20 ~30
SNPs
0.05
0.01
.86
.78
.89
.82
.86
.79
.88
.80
.88
.79
.84
.75
.85
.74
.86
.75
.86
.75
.87
.76
.84
.73
.85
.74
  Set5 20
genes
36~49
SNPs
0.05
0.01
1.0
.99
.99
.97
1.0
.99
1.0
.99
1.0
.99
.79
.69
.80
.71
.80
.72
.82
.72
.82
.73
.79
.69
.79
.68