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Table 1 Performance of our method (DBAC) in comparison with using all atomic contact (AC) and Robetta

From: DBAC: A simple prediction method for protein binding hot spots based on burial levels and deeply buried atomic contacts

Method

Sensitivity

Precision

Specificity

Accuracy

F1

p-value

DBAC

0.58

0.6744

0.9327

0.8643

0.6237

3.0280×10–12

AC

0.32

0.5333

0.9327

0.8140

0.4

1.2849×10–5

Robetta

0.44

0.3667

0.8173

0.7442

0.4

5.3817×10–8

FoldX

0.5

0.4630

0.8606

0.7907

0.4808

6.2451×10–11