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Figure 6 | BMC Systems Biology

Figure 6

From: A trigger model of apoptosis induced by tumor necrosis factor signaling

Figure 6

Dependence of resistance and effective coefficients on the activation efficiencies Dependence of resistance and effective coefficients on the activation efficiencies of caspase-8 (A-B) and caspase-3 (C-D). (A-B) The parameters were chosen from 10-5 <v1, and 10 <K1(= K2) < 1000, and other parameters were taken from Table 1. For each set of parameters, the model equations were solved to obtain the resistance and effective coefficients, which are represented by one point in the figure. (C-D) The parameters were chosen from 10-5 <v2, v3, dcasp3* < 10-2 and 1 <K3 < 100, and other parameters were taken from Table 1.

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