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Table 1 Part of the results of single parameter perturbation analysis.

From: An improved kinetic model for the acetone-butanol-ethanol pathway of Clostridium acetobutylicum and model-based perturbation analysis

P +5%

P -5%

P

Enz

Rd

P

Enz

Rd

Vmax19

BDH

0.0076

Vmax19

BDH

-0.0082

Vmax17

BK

0.0061

Vmax17

BK

-0.0063

Vmax18

PTB

-0.006

Vmax18

PTB

0.0063

Vmax14

B-C-B

0.0076

Vmax14

B-C-B

-0.0082

Vmax11

AAD

-0.0003

Vmax11

AAD

0.0003

Vmax7

AK

0.0054

Vmax7

AK

-0.0054

Vmax9

PTA

-0.0012

Vmax9

PTA

0.0012

Vmax15

CoATa

-0.0072

Vmax15

CoAT

0.0074

Vmax8

CoATb

-0.0002

Vmax8

CoAT

0.0002

Vmax1

PTS

0.0088

Vmax1

PTS

-0.0088

  1. This table lists part of the results of perturbation tests on single kinetic parameters. Here “P” denotes the parameter perturbed. “Enz” denotes the corresponding enzyme. “+/- 5%” indicates up/down-shifting the parameter value by 5%. “B-C-B” stands for enzyme series BHBD-CRO-BCD. Subscripts “a” and “b” indicate there are 2 CoA transferases catalyzing R8 and R15 and here we took them in uniform.