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Figure 1 | BMC Systems Biology

Figure 1

From: TF-Cluster: A pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM)

Figure 1

The clusters identified by Triple-Link are well connected between any nodes within each cluster. 1A: Cluster 1 (yellow nodes) contains the TFs predicted to be involved in pluripotency in human embryonic stem cells. The three genes in the center are master TFs, NANOG, POU5F1, and SOX2, which are crucial for pluripotency. A few nodes located immediately outside the inner ring are those that may not be always captured, depending on the parameters used. 1B: Cluster 7 (yellow nodes) contains the TFs controlling root growth in Arabidopsis under salt stress.

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BMC Systems Biology

ISSN: 1752-0509

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