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Table 1 Simulation and literature results for the GAL network in S. cerevisiae

From: Modeling the evolution of a classic genetic switch

  

Simulation

 

Literature

Gene

# molecules (uninduced)

#molecules (induced)

Fold-increase

Fold-increase

GAL1

2567 +/- 494

270810 +/- 20757

105

100-1000 [5,6,9]

GAL2

1010 +/- 329

119130 +/- 8467

118

100-1000 [5,6]

GAL3

5791 +/- 254

29410 +/- 1810

5

3-5 [5,6]

GAL4

755 +/- 75

750 +/- 66

1

1

GAL80

1101 +/- 94

6390 +/- 449

6

5-10 [5,6]

  1. Mean numbers of molecules +/- standard deviation is reported from equilibrium protein distributions of 100 simulations in very low galactose (uninduced) or very high galactose (induced).
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BMC Systems Biology

ISSN: 1752-0509

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