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Table 1 Impact of the NF-ÎşB Pathway

From: Heterogeneity reduces sensitivity of cell death for TNF-Stimuli

 

TNF

30 ng/ml

10 ng/ml

3 ng/ml

1 ng/ml

Continuous

Death rate

+1.46%

+1.59%

+2.93%

+8.15%

 

Median time of death

-6.25%

-6.85%

-8.55%

-10.6%

 

Relative std

-57.9%

-53.3%

-34.1%

-18.3%

Pulse

Death rate

+11.7%

+13.5%

+19.0%

+35.2%

 

Median time of death

+0.99%

+0.37%

+3.27%

+3.52%

 

Relative std

+3.84%

+8.91%

-2.72%

-0.80%

  1. Comparison of NF-ÎşB knockout cells and wild type cells for different stimulations (continuous and 30 minute pulse of TNF at concentrations of 1, 3, 10 or 30 ng/ml). Death rate, median time of death and standard deviation normalized by the median (relative std) are shown here for the knockout cells normalized by the corresponding wild type cell value.