Table 1 Data sets included in the host response compendium

Influenza A H1N1

r1918, 2:6 r1918 (1918 HA, NA in Tx91), 5:3 r1918 (1918 HA, NA, M, NP, S in Tx91), Tx91 (A/Texas/36/91)

BALB/c

1, 3, 5 dpi

0% survival (with r1918, 2:6 r1918, 5:3 r1918), 100% survival (with Tx91)

Kash 2006 [30],

Tumpey 2005 (for outcome data)[31]

Influenza A H1N1

r1918, PR8

C57BL/6

1, 3, 5 dpi

0% survival (with r1918), 65% survival (with PR8)

Goodman 2009 [32]

Influenza A

H3N2

HKx31 (A/HKx31)

BABL/c, C57BL/6

30 hpi

45% survival (in BALB/c), 80% survival (in C57BL/6)

Ding 2008 [33], Toth 1995 (for outcome data)[34]

Influenza A

H5N1

HK213 (A/Hong Kong/213/03)

C57BL/6, DBA/2J,

3 dpi

0% survival (in DBA/2J), 30% survival (in C57BL/6)

Boon 2009 [35]

Influenza A H5N1

HK483 (A/HK/483/97), HK486 (A/HK/486/97), HK486PB2MT (A/HK/486 PB2-627K/97)

BALB/c

2, 4 dpi

0% survival (with HK483, HK486PB2MT), 25% (with HK486)

Fornek 2009 [36]

Influenza A H5N1

VN/1203 (Vietnam/1203/04), r1918 (H1N1)

SvEv129

1, 3, 4 dpi

0% survival (with VN/1203, r1918)

Cilloniz 2010 [37]

Mengovirus

vMC0 (UV-inactivated mengovirus)

BALB/c

18 hpi

100% survival

Rosenthal unpub.

RSV

A2

BALB/c

1, 3 dpi

100% survival

Janssen 2007 [38]

RSV

A2

B6:129PF1/J

1 dpi

100% survival

Minor 2010 [39]

SARS-CoV

Urbani

BALB/c (young, aged)

1, 2, 5, 7 dpi

100% survival (in young, aged)

Baas 2008 [40]

SARS-CoV

icUrbani, icGZ02, icHC/SZ/61/03

BALB/c AnNHsd (young, aged)

12 h, 1, 3 dpi

0% survival (in aged with icHC/SZ/61/03), 40% survival (in aged with icGZ02), 100% survival (in young with all 3 virus strains, in aged with Urbani)

Rockx 2009 [41]

SARS-CoV

MA15

129

2, 5, 9 dpi

100% survival

Zornetzer 2010 [42]

Influenza A H1N1

A/CA/04/2009, MA1 (a mouse-adapted strain of A/CA/04/2009)

BALB/c

1, 3, 5 dpi

0% survival (with MA1), 100% survival (with A/CA/04/2009)

Josset in preparation