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Table 2 Kinetic constants for NRP2 interactions

From: Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies

 

Measured parameters

Model parameters

 

Value

Unit

Value

Unit

k on,V165,N 2

106

M-1 s-1

1.92 × 10-3

(pmol/cm3 tissue)-1 s-1

k c,V165 R2,N 2

3.1 × 1013

(mol/cm2)-1 s-1

2.02 × 10-2

(pmol/cm3 tissue)-1 s-1

k c,V165 N 2,R2

1014

(mol/cm2)-1 s-1

7.06 × 10-2

(pmol/cm3 tissue)-1 s-1

k c,R1,N 2

1014

(mol/cm2)-1 s-1

7.06 × 10-2

(pmol/cm3 tissue)-1 s-1

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BMC Systems Biology

ISSN: 1752-0509

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