Skip to main content
Figure 1 | BMC Systems Biology

Figure 1

From: Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines

Figure 1

Types of association modules. From top-left to bottom-right: cis-acting effects with copy number variations of chromosomal segments, trans-acting effects with copy number variations of chromosomal segments, associations with gene mutations, associations with DNA methylations, regulatory effects with microRNAs, regulatory effects with transcription factors. Black solid lines: information flows from central dogma. Green dashed lines: regulatory links from transcription factors or microRNAs to their targets on other chromosomal locations. Red dotted lines: associations between observed aberrations and mRNA/microRNA expressions. Arrows indicate positive associations and bar-ends indicate negative associations.

Back to article page