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Table 3 PLP decomposition results showing the subset of EFM with highest correlation with the envirome (as denoted by the r2 and p-value).

From: Projection to latent pathways (PLP): a constrained projection to latent variables (PLS) method for elementary flux modes discrimination

EFM

# LV

r2

p-value

Var(λ)

Var(R)

179

4

0.95

1.14E-32

88.90

52.60

1

4

0.89

5.16E-23

79.90

57.30

210

4

0.87

1.56E-20

65.90

57.80

173

4

0.82

8.78E-17

62.40

58.30

116

4

0.82

2.49E-16

58.40

58.70

139

4

0.86

1.34E-19

52.50

58.90

206

4

0.92

2.14E-27

73.90

60.20

143

4

0.86

9.71E-20

66.70

60.60

69

4

0.82

1.04E-16

57.30

61.00

72

4

0.84

3.52E-18

57.80

61.30

4

4

0.92

1.96E-27

81.40

64.10

68

4

0.81

3.96E-16

60.20

64.80

11

4

0.91

4.16E-25

76.80

79.20

6

4

0.94

1.99E-30

84.60

80.90

7

4

0.82

1.72E-16

59.10

81.60

12

4

0.83

1.52E-17

58.30

82.10

2

4

0.85

7.26E-19

71.00

82.50

  1. Var(λ i ) and Var(R) are % of explained variance of EFM weighting factors and flux data, respectively.