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Figure 4 | BMC Systems Biology

Figure 4

From: A conceptual cellular interaction model of left ventricular remodelling post-MI: dynamic network with exit-entry competition strategy

Figure 4

Effects of interaction strength on the stability of the dynamic network with different interaction matrix ( P A ∈ (0, 1)) Figure 4 shows the evolutionary dynamics with interaction matrix as [0 1; 1 0], k=4, and initial populations of type A and C cells are set as 9900 and 100 in a total population of 10000, respectively. The intensity of selection ω equals to 0.01. Variable Ṗ A is negative when the initial status of P A stays in the region between the marked root (red square) and 1 in the left part of the figure(Left). When P A goes to the marked root, Ṗ A reaches 0. Accordingly, the population of type A cells decreases in the interval of [root, 1] until P A goes to the root denoted at 0.5 in the simulation. The simulation results shown in the right part of the figure (Right) demonstrate that the population of type A cells approached 5000 within 1000 generations.

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