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Table 2 Illustrative highly disordered Pfam domains of archaean origin

From: Archaic chaos: intrinsically disordered proteins in Archaea

Name

Domain

Description

% D

NOP10_SULSO

1-53

nucleolar protein essential for normal 18S rRNA production and rRNA pseudouridylation

41

PUR2_METJA

1-102

related to the N-terminal domain of biotin carboxylase/carbamoyl phosphate synthetase

42

O27142_METTH

17-302

tldD and pmbA proteins, found to suppress mutations in letD and inhibit of DNA gyrase

44

Y2068_ARCFU

10-100

transmembrane region of Cytochrome C biogenesis protein believed to bind double-stranded DNA

64

RF1_METTH

2-137

eRF1 stops protein biosynthesis by recognising stop codons and stimulating peptidyl-tRNA hydrolysis

81

Y2677_METMA

7-59

CsbD, a bacterial general stress response protein

100

MTPE_SULTO

1-56

epsilon subunit of the ATP synthase, a potent inhibitor of ATPase activity

100

Q48297_HALSA

295-353

helical bundle domain, homodimer interface of the signal transducing histidine kinase family

100

Q8TTT9_METAC

235-302

NosD, a periplasmic protein thought to insert copper into the exported reductase apoenzyme

100