Figure 4
From: Identifying essential genes in bacterial metabolic networks with machine learning methods
The non-mevalonate pathway. The non-mevalonate pathway produces isopentenyl diphosphate (IPP). It is an alternative pathway in bacteria and does not exist in the human host which uses the mevalonate pathway to produce IPP. The non-melavonate pathway was highly enriched with genes that were predicted to be essential. Reactions are given by their EC number and the gene symbol of the genes of the corresponding enzymes.