Figure 1From: Two additive mechanisms impair the differentiation of 'substrate-selective' p38 inhibitors from classical p38 inhibitors in vitroSingle substrate assay. Phospho-MK2 (Δ) or phospho-ATF2 (▽) was measured at 30 min or 120 min, respectively in the single substrate assay. Data are shown as a fraction of the maximum signal for varying amounts of compound treatment: A, SD-0006, B, BIRB 796, C, CMPD1. IC50 values for each compound/substrate are listed in Table 1. Data is shown ± standard deviation (n = 2)Back to article page