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Table 3 13 Modules in gene coexpression network in Figure 2 with their enriched pathways.

From: Integrated analysis of mutations, miRNA and mRNA expression in glioblastoma

Module

Module color

Pathway category

Name

P-value

1

Purple

Cell signaling

Ion channel and phorbal esters signaling

8.60E-03

2

Wind

stawberry

Apoptosis

Apoptotic DNA fragmentation and tissue homeostasis

3.52E-02

  

Cell cycle regulation

Activation of Src by protein-tyrosine phosphatase alpha

4.23E-02

  

Cell cycle regulation

AKAP95 role in mitosis and chromosome dynamics

4.98E-02

  

Cell cycle regulation

Sonic Hedgehog (SHH) Receptor Ptc1 regulates cell cycle

4.23E-02

3

Forest green

Translation

Ribosome

3.32E-09

4

Teal blue

Metabolism of cofactors and vitamins

One carbon pool by folate

4.72E-02

5

Black

Cell signaling

Ca++/Calmodulin-dependent protein kinase Activation

3.59E-03

6

Green

yellow

Immunology

Cells and molecules involved in local acute inflammatory response

4.68E-02

7

Yellow

Cell growth and death

Cell cycle

2.62E-02

8

Orange

Immunology

Classical complement

2.85E-02

9

Lavender

Cell signaling

IFN alpha signaling

1.03E-02

10

Blue

Cell activation

Th1/Th2 differentiation

3.79E-02

11

Olive green

Metabolism

Electron transport reaction in mitochondria

1.31E-02

  

Energy metabolism

Oxidative phosphorylation

9.00E-03

  

Neuro-degenerative diseases

Parkinson's disease

8.67E-03

12

Maroon

Translation

Ribosome

1.13E-03

13

Red

Metabolism/Neuroscience

Vitamin C in the brain

9.11E-03

  

Cell activation

Angiotensin-converting enzyme 2 regulates heart function

1.27E-02

  

Metabolism

Intrinsic prothrombin activation

3.83E-02

  

Metabolism

Platelet amyloid precursor protein

1.47E-02

  

Hematopoiesis

Regulators of bone mineralization

2.58E-03