Figure 7

Number of essential gene pairs predicted using iNJ 661m and iNJ 661v. Flux balance analysis of iNJ 661m under in vivo conditions predicted 78 essential gene pairs, whereas iNJ 661v predicted 166 essential gene pairs. There were 35 gene pairs predicted to be essential by both network descriptions; 131 gene pairs were only predicted to be essential using iNJ 661v, whereas 43 gene pairs were only predicted to be essential using iNJ 661 m. Most of the jointly predicted gene pairs were involved in amino acid and nucleotide metabolism.