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Table 1 Genes differentially expressed with lithium treatment

From: A genetic network model of cellular responses to lithium treatment and cocaine abuse in bipolar disorder

  

Microarray

Unigene

rt-QPCR

EntrezID

Gene

Fold Change

Corrected P-value

Brain exp per 1 M transcripts

Fold Change

P-value

1316

KLF6

1.24

3.77E-02

70

  

1396

CRIP1

1.29

1.42E-05

3

1.58

2.31E-02

1843

DUSP1

1.57

1.17E-02

53

  

2353

FOS

1.88

4.87E-09

461

2.02

1.63E-05

2354

FOSB

1.53

3.32E-03

32

  

4921

DDR2

-1.25

5.02E-04

21

-1.15

4.61E-01

4929

NR4A2

1.36

4.22E-03

134

1.42

3.07E-02

5997

RGS2

1.23

2.57E-02

25

  

8614

STC2

-1.24

1.41E-03

22

-1.50

4.22E-03

28984

RGC32

1.55

5.19E-06

58

1.58

2.40E-03

29923

HIG2

-1.35

4.20E-04

33

  

118429

ANTXR2

1.27

1.05E-03

25

  
  1. 12 genes were significantly differentially expressed (Bonferroni corrected p-value ≤ 0.05 and fold change ≥ +/- 20%) in the microarray experiment. All of these genes are expressed in brain tissue (UniGene), and rt-QPCR results are consistent with the microarray results in both direction and approximate magnitude.
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BMC Systems Biology

ISSN: 1752-0509

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