Figure 4From: Minimally perturbing a gene regulatory network to avoid a disease phenotype: the glioma network as a test caseThe glioma network. Genes (ovals) and their alternative regulation functions (rectangles) are bordered by frames of the same color. Ovals contain the name of the relevant human gene, following the nomenclature in [48]. Rectangles contain the name of the regulation function [49]. Regulation functions are connected by directed edges to the gene they regulate. Regulators are connected by directed edges to the regulation functions in which they are involved. The figure was generated using Cytoscape [59]. The bold arrows indicate the two entities that constitute the prohibited phenotype (see text).Back to article page