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Figure 2 | BMC Systems Biology

Figure 2

From: Systems genetics analyses predict a transcription role for P2P-R: Molecular confirmation that P2P-R is a transcriptional co-repressor

Figure 2

Characteristics of the P2P-R-associated transcription network in fat cells. Of the transcription network of 75 gene transcripts in fat cells, the 34 that are co-expressed with a correlation coefficient of ≥ 0.75 are illustrated as a robust transcription network. The color of the lines connecting the 34 gene transcripts indicate the degree to which their expression co-varies among the strains evaluated (red = very high positive correlation, orange = moderate positive correlation, blue = very high negative correlation; green = moderate negative correlation). At the core of this network a group of 10 transcripts that show the most numerous associations is evident. These key transcription network components include: P2P-R (Rbbp6), Atf1, Thrap5, Crsp9, Zfml, Pura, Dr1, Gtf2e2, Maml1 and Cnot7.

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