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Table 3 Significant biological pathways in the set of zero TO genes between regions.

From: Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks

Region comparison

Pathways

p value (FDR = 0.05)

EC-HIP

Bacterial infections in CF airways

1.27e-4

 

Transcription NF-kB signalling pathways

1.46e-4

 

Immune response MIF in innate immunity response

2.34e-4

 

G-protein signalling RhoB regulation pathway

3.09e-4

 

Immune response-bacterial infections

7.75e-4

 

Toll-like receptor signalling pathway leading to proinflammatory response

9.02e-4

EC-MTG

TGF, WNT and cytoskeleton remodelling

4.51e-4

 

Transport Rab-9 regulation pathway

1.48e-3

EC-PCC

Immune response-Function MEF2 in T lymphocytes

9.40e-4

 

Plasmin signalling

3.51e-3

HIP-MTG

Transport Rab-3 regulation pathway

6.52e-3

 

Intracellular cholesterol transport

6.56e-3

HIP-PCC

Neurophysiological process - Dopamine D2 receptor transactivation of PDGFR in CNS

9.64e-4

 

TGF beta mediated regulation of cell proliferation

1.95e-3

PCC-MTG

Sorting endosome formation in CF

2.51e-4

 

Role of inhibitor of apoptosis (IAP) proteins

1.23e-2