Parameter | Value | Description |
---|---|---|
ka | 0.0003 | Notch (N)/Delta (D) binding rate |
kd | 0.12 | Bound complex (B) unbinding rate |
dB | 0.19 | Bound complex (B) decay rate |
aBN | 0.01 | Bound complex (B) regulation of Notch (N) |
bBN | 1 | Bound complex (B) regulation of Notch (N) |
cBN | 1 | Bound complex (B) regulation of Notch (N) |
hBN | -2 | Bound complex (B) regulation of Notch (N) |
bON | 1 | Ovol2 (O2) regulation of Notch (N) |
cON | 0.5 | Ovol2 (O2) regulation of Notch (N) |
hON | 2 | Ovol2 (O2) regulation of Notch (N) |
dN | 0.03 | Notch (N) decay rate |
aND | 0.01 | Notch (N) regulation of Delta (D) |
bND | 1 | Notch (N) regulation of Delta (D) |
cND | 10 | Notch (N) regulation of Delta (D) |
hND | 2 | Notch (N) regulation of Delta (D) |
dD | 0.006 | Delta (D) decay rate |
aVO | 0.1 | Ovol1 (O1) regulation of Ovol2 (O2) |
bVO | 2 | Ovol1 (O1) regulation of Ovol2 (O2) |
cVO | 1 | Ovol1 (O1) regulation of Ovol2 (O2) |
hVO | 2 | Ovol1 (O1) regulation of Ovol2 (O2) |
bGO | 1 | TGF-β (G) regulation of Ovol2 (O2) |
cGO | 1 | TGF-β (G) regulation of Ovol2 (O2) |
hGO | 1 | TGF-β (G) regulation of Ovol2 (O2) |
dO | 1 | Ovol2 (O2) decay rate |
bOV | 2 | Ovol2 (O2) regulation of Ovol1 (O1) |
cOV | 1 | Ovol2 (O2) regulation of Ovol1 (O1) |
hOV | 2 | Ovol2 (O2) regulation of Ovol1 (O1) |
bAV | 1 | Basement adhesion (A) regulation of Ovol1 (O1) |
cAV | 1 | Basement adhesion (A) regulation of Ovol1 (O1) |
hAV | 1 | Basement adhesion (A) regulation of Ovol1 (O1) |
dV | 1 | Ovol1 (O1) decay rate |
aOM | 0.1 | Ovol2 (O2) regulation of c-Myc (M) |
bOM | 1 | Ovol2 (O2) regulation of c-Myc (M) |
cOM | 1 | Ovol2 (O2) regulation of c-Myc (M) |
hOM | 1 | Ovol2 (O2) regulation of c-Myc (M) |
dM | 1 | c-Myc (M) decay rate |